The Mudumalai National Park and Wildlife Sanctuary also a declared tiger reserve, lies on the northwestern side of the Nilgiri Hills (Blue Mountains), in Nilgiri District, about 150 kilometres (93 mi) north-west of Coimbatore city in Tamil Nadu, India. It shares its boundaries with the states of Karnataka and Kerala. The sanctuary is divided into five ranges – Masinagudi, Thepakadu, Mudumalai, Kargudi and Nellakota.

The protected area is home to several endangered and vulnerable species including Indian elephant, Bengal tiger, gaur and Indian leopard. There are at least 266 species of birds in the sanctuary, including critically endangered Indian white-rumped vulture and long-billed vulture.

The Western Ghats Nilgiri Sub-Cluster of 6,000 square kilometres (2,300 sq mi), including all of Mudumalai National Park, is under consideration by the UNESCO World Heritage Committee for selection as a World Heritage Site.